Polynucleotides are an advanced, non-invasive treatment in regenerative and pro-aging aesthetics, designed to improve skin quality, hydration, and elasticity at a cellular level. This innovative injectable treatment works by stimulating fibroblast activity, naturally increasing collagen and elastin production to restore healthier, more radiant skin.
Polynucleotides are particularly effective for:
Reducing fine lines and wrinkles
Improving skin hydration and glow
Smoothing skin texture and tone
Minimising dark under-eye circles, puffiness, and hollowness
Protecting skin from free radical damage and environmental stress
This treatment is ideal for delicate areas such as the under-eyes, face, neck, and décolletage, making it a versatile solution for patients seeking natural skin rejuvenation without downtime.
Improvement in dark circles
Glowing hydrated skin
Approx 15-20 minutes
1-2 days
Results should last 6-9 months.
Dr Fiona McCarthy is the Founder & Medical Director of The Bronte Clinic. As a NHS consultant physician, she has over 25 years of medical experience and is a keen advocate of a measured & evidence-based approach to aesthetic treatments. Dr Fiona sees patients both in our London & Surrey clinics.
Dr Alpa Kanji is a Consultant Dermatologist at Guys & Thomas’ NHS Trust. She sees patients for a wide variety of medical dermatology conditions including eczema, psoriasis, acne, pigmentation disorders as well as providing mole checks and skin cancer screening.
Jessica Foreman is our experienced Advanced Nurse Practitioner and sees patients in our Surrey clinic. Jessica is passionate about the transformative effect that improving skin health can have on a person’s confidence and self-esteem. In addition to her aesthetic practice, she continues to work as an Advanced Nurse Practitioner within the NHS.
Dr Carole Reid combines her aesthetic practice at The Bronte Clinic with a career in Emergency Medicine. Aesthetic Medicine is a natural fit for her, marrying the creativity and aesthetic flair of her previous career in fashion with the scientific and academic rigour of medicine.She derives huge satisfaction working between A&E and aesthetics and most enjoys talking with patients and helping them feel their best.
Polynucleotide injections are well-tolerated and minimally uncomfortable for most patients. You may feel a light pinching or mild stinging sensation during the injection, particularly in delicate areas such as the under-eyes or décolletage, but any discomfort is brief and manageable. Thanks to their gentle formulation, polynucleotide skin treatments are ideal for sensitive skin and areas prone to bruising or swelling. There is minimal downtime, with most patients returning to normal activities the same day.
Topical anaesthetic is available if necessary.
The procedure itself takes no more than 10 minutes. However a thorough medical consultation is required prior to this to ensure this is the right treatment for you.
You can expect to see visible improvements in skin hydration, texture, and radiance within 7 to 10 days after your first polynucleotide treatment. However, the full benefits—including firmer, smoother, and more youthful-looking skin—develop gradually over 3 to 6 weeks as your skin produces more collagen and elastin.
For the best and most long-lasting results, we recommend a course of 2-3 polynucleotide treatments, spaced 2–4 weeks apart. Continued improvement is seen in the weeks following your final session as the skin continues its natural regeneration process.
Results from polynucleotide skin treatments typically last 6 to 9 months, depending on your skin type, age, lifestyle, and skincare routine. As collagen and elastin production is gradually stimulated, the skin becomes firmer, more hydrated, and visibly more radiant over time. Many patients choose to have maintenance treatments every 6 months to sustain and enhance their results.
58 South Molton St,
Mayfair,
W1K 5SL
Tel: 0203 4882582
54 Quarry St,
Guildford
GU1 3UA
Tel: 0203 4882582
