Collagen or Hyaluronic Acid: Which Is Best for Anti-Aging?

Click the link below to download the complete Press Release file for Collagen or Hyaluronic Acid: Which Is Best for Anti-Aging?
Read Press Release

Vogue settles the collagen-versus-hyaluronic-acid debate by concluding it isn’t really a competition: the two ingredients do different jobs. According to dermatological doctor Dr Nora Jaafar, collagen loss is a key biological driver of aging while hyaluronic acid loss is a key visual contributor, one affects the skin’s structure, the other its hydration.

Collagen, the body’s most abundant protein, provides the skin’s structural framework, but production declines by about 1% a year from our mid-twenties. Dr Fiona McCarthy, Medical Director and Founder of The Bronte Clinic and a consultant medical oncologist, notes this decline accelerates during perimenopause, leading to sagging, deepening lines, and loss of facial definition. Crucially, topical collagen can’t rebuild structure, the molecule is too large to penetrate the skin barrier — though supplements have stronger evidence, with the largest review to date (January 2026) linking them to improved skin, musculoskeletal health, and osteoarthritis outcomes.

Hyaluronic acid, a humectant that holds up to 1,000 times its weight in water, plumps and hydrates with results visible within minutes to hours. However, Dr McCarthy cautions the effects are transient, depend on continual use, and don’t rebuild the skin’s deeper architecture. Formulation matters too: the best products combine multiple molecular weights, and concentration should sit between 1–2%, as anything higher can paradoxically dehydrate the skin.

For genuine collagen stimulation, both experts point to retinoids as the gold standard, with peptides (particularly matrikines) also well supported, though results take at least three months. And the single most important anti-aging product of all? Daily SPF, since UV radiation is the biggest driver of collagen degradation.

The recommended routine: AM, antioxidant serum, hyaluronic acid serum, moisturiser, and broad-spectrum SPF 50; PM, retinoid, peptide-based treatment, and a hydrating moisturiser. Bottom line: use both ingredients together, hyaluronic acid for immediate hydration, collagen-supporting ingredients for long-term structure.

Read the full article

Tags

Effective Treatments

A young woman with long dark hair smiles gently, resting her face on her hand. She is wearing a white sleeveless top and is looking directly at the camera, with a soft blue background behind her.

Profhilo®

Profhilo® is an innovative, injectable skin bio-remodelling treatment designed to deeply hydrate the skin and improve overall skin quality, firmness, and radiance. Often called the “injectable moisturiser”, Profhilo® delivers high concentrations of pure hyaluronic acid to rejuvenate dry, dull, or ageing skin from within.

This non-surgical skin treatment involves five carefully placed injections on each side of the face, delivering the hyaluronic acid just beneath the skin’s surface. Profhilo® then spreads evenly through the tissues, stimulating collagen and elastin production to improve skin elasticity, texture, and tone.

Profhilo® is ideal for improving:

  • Dehydrated and crepey skin
  • Skin laxity and loss of firmness
  • Dull or tired-looking complexion
  • Fine lines and overall texture

It is most commonly used on the face, neck, and décolletage, but is also highly effective on areas such as the hands, upper arms, and knees, where skin thinning and dryness are a concern.

For best results, we recommend a course of 2 Profhilo® treatments, spaced approximately 4 weeks apart, with maintenance every 6 months to sustain the glow.

Book nowRead more
A young woman with curly dark hair and clear skin looks directly at the camera, smiling softly. She has bare shoulders and is posed against a plain, light grey background.

Profhilo® Structura

As we age, the loss and redistribution of facial fat pads (adipose tissue) can lead to hollow cheeks, sagging skin, and jowl formation. Profhilo® Structura is an advanced injectable treatment that addresses this volume loss by rejuvenating the deeper layers of the skin and stimulating the regeneration of facial fat tissue.

Unlike traditional dermal fillers, Profhilo® Structura uses a unique combination of high and low molecular weight hyaluronic acid to support natural facial structure and contour from within, enhancing volume in a subtle, refined way.

Profhilo® Structura is ideal for:

  • Mid-face volume loss
  • Hollow cheeks and under-eye areas
  • Sagging skin and jowls
  • Loss of definition in the jawline
  • General signs of facial ageing due to fat loss

For best results, we advise a course of 2 Profhilo® Structura treatments, spaced 4 weeks apart.

Book nowRead more
A young woman with long dark hair smiles at the camera. She is wearing a light pink ribbed jumper and stands against a plain white background.

Skin Boosters

Skin boosters are a highly effective treatment designed to deeply hydrate the skin, improve texture, and restore a natural glow. Unlike traditional dermal fillers, skin boosters do not add volume—instead, they deliver microinjections of hyaluronic acid or other nourishing ingredients directly into the skin to enhance hydration, elasticity, and luminosity from within.

Ideal for treating dull, dehydrated, or crepey skin, skin boosters are commonly used on the face, neck, décolletage, and hands, and are also suitable for areas like the under-eyes and acne-scarred skin. Results include smoother, firmer, and more radiant skin, with minimal downtime and natural-looking improvement.

For best results, we usually recommend a course of 2–3 treatments spaced 3–4 weeks apart, followed by maintenance every 6 months.

Book nowRead more
Close-up of a smiling woman gently touching her face with both hands, showing clear skin and blue eyes. The background is neutral, and the lighting is soft.

Dermal Fillers

As we age, natural facial volume loss can lead to a tired, sunken appearance and the development of static lines and wrinkles which are visible even when the face is at rest. Dermal fillers are an effective, non-surgical way to restore volume, smooth deep lines, and rejuvenate facial contours with natural-looking results.

Dermal fillers are made of hyaluronic acid, a substance found naturally in the body that helps maintain hydration, structure, and the youthful plumpness of the skin. These fillers are gradually broken down by the body, with results typically lasting 12 to 18 months, depending on factors like metabolism, lifestyle, and treatment area.

Areas that can be treated with dermal fillers:

  • Under-eye hollows and tear troughs
  • Cheek and mid-face volume loss
  • Lips – for subtle shape and definition
  • Marionette lines and nasolabial folds
  • Jawline and chin definition

A thorough medical consultation is required prior to any dermal filler treatment to ensure your safety and suitability, and to tailor your treatment plan to your unique facial structure and aesthetic goals.

Book nowRead more